A new generation of peroxyacetic-acid- based disinfectants along with a safer handling solution
In chemical science peroxyacetic acid (POAA) is known for about a hundred years. In 1902 Freer & Novy reported the excellent microbicidal and especially sporicidal efficacy of dilute peroxyacetic acid that was prepared from diacetyl peroxide [1]. Only 10 years later D’ans & Frey succeeded to synthesise POAA [2].
In the mid 60s of the last century, Sproessig & al. surveyed POAA for medical use in the former GDR [3,4]. But still any use of this highly efficient disinfectant on a larger scale and outside laboratory environments was inhibited, because POAA was only available as a 40 % solution in glacial vinegar (anhydrous acetic acid). This is a very corrosive, flammable and even explosive preparation that has to be stored at temperatures below 0°C. 1). 2).